Iontophoresis for Hyperhidrosis: How It Works and Why It Helps

For many people with hyperhidrosis, a condition that causes excessive sweating, finding an effective treatment can feel like a long and frustrating journey.  

While antiperspirants and lifestyle adjustments can sometimes help, those with more persistent or severe symptoms often need something stronger. This is where iontophoresis comes in. 

Used by dermatologists for decades and recommended by the NHS for treating excessive sweating of the hands and feet, iontophoresis is a well-established, drug-free treatment option that offers real relief for many people. 

But what exactly is it, how does it work, and why is it considered so effective? 

What is Iontophoresis? 

Iontophoresis is a non-invasive treatment that uses a gentle electrical current to reduce or stop sweating in specific areas of the body. It's most commonly used on the hands, feet, and underarms, the areas most commonly affected by primary focal hyperhidrosis. 

The process involves placing the affected area (such as your hands or feet) in a tray of water through which a low-voltage electrical current is passed. Soaked pads are used instead for underarm treatment. Treatment sessions typically last between 15 and 30 minutes and are repeated several times a week over a few weeks. Once sweating is under control, maintenance sessions are usually only required once a week or less. 

How Does Iontophoresis Work? 

Although the exact mechanism isn't fully understood, iontophoresis is thought to work by temporarily blocking the sweat glands. When the electrical current passes through the water and into the skin, it may thicken the outer layer of the skin (stratum corneum) and the tubes (ducts) leading from the sweat glands, preventing sweat from being released. 

It’s important to note that iontophoresis doesn’t cause any damage to the sweat glands; the effect is temporary and reversible, which is why maintenance treatments are necessary to keep symptoms under control. 

Why Is It So Effective? 

One of the most significant advantages of iontophoresis is its high success rate, especially for palmar (hand) and plantar (foot) hyperhidrosis. Studies have shown that around 80–90% of patients experience a significant reduction in sweating after regular use. 

For many people, it provides a long-term solution that doesn’t involve medication, surgery, or permanent changes to the body. When used correctly and consistently, iontophoresis can transform daily life, allowing people to shake hands, wear sandals, hold pens or tools, and go about their routines without the constant interruption and embarrassment of sweat. 

Who Can Benefit? 

Iontophoresis is most recommended for individuals with primary focal hyperhidrosis, which is excessive sweating that isn’t caused by another medical condition and typically affects specific body parts, such as the hands, feet, or underarms. 

It’s generally considered safe for most adults and older children. However, it may not be suitable for people with certain medical conditions, such as those with pacemakers or ICDS, metal implants in the treatment area, or during pregnancy. 

What to Expect 

Treatment can initially feel a little strange; some people describe it as a mild tingling or buzzing sensation. It's not painful, but it may take a few sessions to get used to the process. 

Results aren’t instant, but many people notice a difference after just a few sessions. Once the sweating is under control, the time between treatments can often be extended, making it a manageable part of a long-term treatment plan. 

Used correctly, side effects with iontophoresis are uncommon. 

Final Thoughts 

Hyperhidrosis can have a serious impact on quality of life, from daily discomfort to social anxiety and reduced confidence. While no single treatment works for everyone, iontophoresis offers a safe, effective, and accessible option for many. 

If you think iontophoresis could help, it’s always best to speak with a healthcare professional or specialist support organisation to explore whether it’s right for you. With the right guidance and consistency, it could be a valuable step towards regaining control over excessive sweating.